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Allele vs. Locus: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on December 30, 2023
An allele is a variant form of a gene at a particular locus, which is a specific location on a chromosome.
Allele vs. Locus

Key Differences

An allele is a specific version of a gene, representing variations in a DNA sequence. A locus, on the other hand, refers to the exact location on a chromosome where a gene is found.
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Dec 30, 2023
Alleles contribute to the genetic diversity within a population by presenting different forms of a gene. The locus is a fixed position that determines where a gene or allele can be found on a chromosome.
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Each individual inherits alleles from their parents, which combine to determine traits. The locus for a particular gene remains constant across different individuals, though the alleles at that locus can vary.
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In genetics, alleles are often discussed in terms of dominant and recessive traits. The concept of a locus is crucial for mapping genes and understanding chromosome structure.
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Alleles can mutate, leading to different expressions of a gene. The locus remains unchanged during these mutations, serving as a stable reference point on the chromosome.
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Comparison Chart

Definition

A version of a gene
The specific location of a gene on a chromosome
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Role in Genetics

Determines variations of a trait
Serves as a fixed position for gene mapping
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Variation

Alleles can be different in the same species
The locus is consistent across individuals
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Inheritance

Inherited from parents
The position of the locus is inherited, but not its specific alleles
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Impact on Evolution

Allelic variation contributes to evolution
The locus provides a framework for genetic diversity
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Allele and Locus Definitions

Allele

Represents genetic diversity within a species.
Blood types A, B, and O are caused by different alleles.
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Locus

A key concept in the study of genetics and heredity.
Researchers study the locus to understand hereditary diseases.
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Allele

Can be dominant or recessive.
The allele for brown eyes is dominant over the allele for blue eyes.
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Locus

Used to identify the location of genetic markers.
The locus is essential for identifying genes associated with traits.
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Allele

Undergoes mutations causing variations in traits.
A mutation in the allele can lead to genetic disorders.
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Locus

A specific position on a chromosome.
The locus for the human blood type gene is on chromosome 9.
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Allele

A variant form of a gene.
Blue and brown eye colors are determined by different alleles.
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Locus

Acts as a reference point in genetic mapping.
Geneticists identified the locus for cystic fibrosis on chromosome 7.
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Allele

Contributes to an individual's phenotype.
The alleles for flower color in peas were studied by Gregor Mendel.
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Locus

Stays constant across individuals of a species.
The locus for eye color genes is the same in all humans.
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Allele

Any of the alternative forms of a gene or other homologous DNA sequence. Also called allelomorph.
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Locus

A locality; a place.
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Allele

(genetics) One of a number of alternative forms of the same gene occupying a given position, or locus, on a chromosome.
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Locus

A center or focus of great activity or intense concentration
"the cunning exploitation of loci of power.
The insulation from normal American society" (Clifton Fadiman).
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Allele

One of two or more alternative forms of a gene that can have the same place on homologous chromosomes and are responsible for alternative traits.
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Locus

(Mathematics) The set or configuration of all points whose coordinates satisfy a single equation or one or more algebraic conditions.
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Allele

Either of a pair of Mendelian characters that may occur in an organism as a consequence of variation at one gene locus.
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Locus

The position that a given gene or genetic marker occupies on a chromosome.
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Allele

One of two alternate forms of a gene that can have the same locus on homologous chromosomes and are responsible for alternative traits;
Some alleles are dominant over others
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Locus

A place or locality, especially a centre of activity or the scene of a crime.
The cafeteria was the locus of activity.
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Locus

(mathematics) The set of all points whose coordinates satisfy a given equation or condition. Category:en:Curves
A circle is the locus of points from which the distance to the center is a given value, the radius.
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Locus

(genetics) A fixed position on a chromosome that may be occupied by one or more genes.
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Locus

A passage in writing, especially in a collection of ancient sacred writings arranged according to a theme.
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Locus

A place; a locality.
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Locus

The line traced by a point which varies its position according to some determinate law; the surface described by a point or line that moves according to a given law.
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Locus

The scene of any event or action (especially the place of a meeting)
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Locus

The specific site of a particular gene on its chromosome
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Locus

The set of all points or lines that satisfy or are determined by specific conditions;
The locus of points equidistant from a given point is a circle
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Repeatedly Asked Queries

What does locus mean in genetics?

A locus is a specific position on a chromosome where a gene is located.
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What is an allele?

An allele is a variant form of a gene.
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Is the locus the same in all individuals?

Yes, the locus is a fixed position that is the same in all individuals of a species.
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Can alleles be dominant or recessive?

Yes, alleles can be either dominant or recessive, affecting trait expression.
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What is an example of an allele?

An example is the allele for blue eyes or brown eyes.
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Can loci be used to study genetic disorders?

Yes, loci are crucial in identifying genes linked to genetic disorders.
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What happens during a mutation in an allele?

A mutation in an allele can change the gene's function or trait expression.
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How many alleles can a single gene have?

A gene can have multiple alleles, depending on the variations in a population.
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Can the locus change?

No, the locus is a stable, fixed position on the chromosome.
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How are alleles related to traits?

Alleles determine the different forms a trait can take.
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How do alleles affect genetic diversity?

Alleles contribute to genetic diversity by providing different forms of a gene.
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Can the same locus have different alleles?

Yes, the same locus can have different alleles in different individuals.
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Can environmental factors influence alleles?

Environmental factors can influence the expression of certain alleles.
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Is the number of loci the same in all organisms?

No, the number of loci varies among different organisms and species.
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How is the locus important in genetic mapping?

The locus helps in locating specific genes on chromosomes for genetic studies.
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What is the relationship between alleles and phenotype?

Alleles determine the phenotype, or physical expression, of a trait.
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How is a locus identified in genetic studies?

Loci are identified through genetic mapping and chromosome analysis.
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How do alleles contribute to evolution?

Allelic variation drives evolutionary changes by enabling adaptability.
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What is the role of the locus in heredity?

The locus determines where genes for hereditary traits are located.
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Are loci the same in different species?

No, loci can vary between species.
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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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