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Synthetic Vitamin E vs. Natural Vitamin E: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Updated on December 25, 2023
Synthetic Vitamin E, made artificially, differs in chemical structure from Natural Vitamin E, which is derived directly from plant sources.
Synthetic Vitamin E vs. Natural Vitamin E

Key Differences

Synthetic Vitamin E is manufactured through a chemical process using petroleum products, resulting in a compound called dl-alpha-tocopherol. Natural Vitamin E, however, is directly extracted from plant oils and is known as d-alpha-tocopherol. The difference in their chemical names (dl- vs. d-) highlights their distinct molecular structures.
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Dec 15, 2023
In terms of bioavailability, Synthetic Vitamin E is less potent compared to Natural Vitamin E. This is because the natural form is more readily absorbed and utilized by the human body.
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Regarding antioxidant properties, Natural Vitamin E is more effective. The synthetic form, while still beneficial, does not offer the same level of antioxidant protection as its natural counterpart.
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Synthetic Vitamin E is more stable and has a longer shelf life compared to Natural Vitamin E. This stability makes it a common choice for inclusion in various supplements and fortified foods.
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Cost-wise, Synthetic Vitamin E is generally less expensive to produce than Natural Vitamin E. This cost difference often reflects in the pricing of vitamin E supplements and products containing these forms.
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Comparison Chart

Source of Origin

Chemically synthesized from petroleum products
Extracted from plant oils
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Chemical Structure

Dl-alpha-tocopherol
D-alpha-tocopherol
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Bioavailability

Less bioavailable
More bioavailable
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Antioxidant Efficacy

Less effective
More effective
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Cost

Generally less expensive
More expensive
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Synthetic Vitamin E and Natural Vitamin E Definitions

Synthetic Vitamin E

Synthetic Vitamin E is characterized by its chemical structure, dl-alpha-tocopherol.
The label specifies that this product contains dl-alpha-tocopherol, indicating it's Synthetic Vitamin E.
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Natural Vitamin E

Known for its superior antioxidant properties compared to the synthetic version.
The Natural Vitamin E in this serum provides excellent skin protection.
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Synthetic Vitamin E

Less bioavailable compared to its natural counterpart, Synthetic Vitamin E is still beneficial.
Despite being Synthetic Vitamin E, it still contributes to my daily nutritional needs.
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Natural Vitamin E

Natural Vitamin E is often more expensive due to its natural sourcing and processing.
The high cost of this vitamin is justified by its Natural Vitamin E content.
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Synthetic Vitamin E

Produced through chemical synthesis, it’s a common form of Vitamin E in supplements.
Most over-the-counter vitamins prefer Synthetic Vitamin E due to its cost-effectiveness.
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Natural Vitamin E

Natural Vitamin E is directly extracted from plant oils and known as d-alpha-tocopherol.
This organic supplement boasts Natural Vitamin E sourced from sunflower oil.
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Synthetic Vitamin E

A man-made form of Vitamin E used in supplements and fortified foods.
The multivitamin contains Synthetic Vitamin E to enhance its nutritional value.
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Natural Vitamin E

More bioavailable and effective, Natural Vitamin E is preferred for its potency.
I choose supplements with Natural Vitamin E for better absorption.
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Synthetic Vitamin E

Often found in skincare products due to its stability and affordability.
This lotion uses Synthetic Vitamin E for its antioxidant properties.
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Natural Vitamin E

Typically found in higher-end health products due to its extraction process and benefits.
This premium face cream features Natural Vitamin E for its nourishing qualities.
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Repeatedly Asked Queries

What is Natural Vitamin E?

Vitamin E that is directly extracted from plant oils, known as d-alpha-tocopherol.
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Is Synthetic Vitamin E effective?

Yes, though less bioavailable and potent than Natural Vitamin E, it is still beneficial.
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How are Synthetic and Natural Vitamin E different?

They differ in source, molecular structure, bioavailability, and antioxidant efficacy.
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Why is Natural Vitamin E preferred?

Due to its higher bioavailability, better antioxidant properties, and natural sourcing.
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What is Synthetic Vitamin E?

A man-made form of Vitamin E, known as dl-alpha-tocopherol, used in various supplements.
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Can Synthetic Vitamin E meet daily vitamin needs?

Yes, it can contribute to meeting daily vitamin requirements.
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Is Natural Vitamin E better for skin?

It is often considered superior for skin due to its natural form and antioxidant properties.
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Are there any side effects of Synthetic Vitamin E?

High doses might lead to certain side effects, but generally, it is well-tolerated.
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Can Synthetic Vitamin E cause allergies?

Allergic reactions are rare but possible, particularly in sensitive individuals.
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Is Natural Vitamin E more expensive?

Yes, typically it is more expensive due to its extraction and processing methods.
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Why is Synthetic Vitamin E used in skincare?

Its stability and lower cost make it a practical choice for skincare formulations.
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Can I get enough Vitamin E from natural foods?

Yes, many foods naturally rich in Vitamin E can meet daily requirements.
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How do I know if a product contains Synthetic Vitamin E?

Look for dl-alpha-tocopherol on the ingredient list.
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Are there vegan sources of Natural Vitamin E?

Yes, plant oils, nuts, and seeds are vegan-friendly sources.
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Should I choose supplements with Natural or Synthetic Vitamin E?

It depends on personal preference, budget, and health goals. Natural Vitamin E is generally considered superior in terms of bioavailability and effectiveness.
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Can Natural Vitamin E improve skin health?

Yes, its antioxidant properties are beneficial for skin health.
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What foods are rich in Natural Vitamin E?

Foods like nuts, seeds, and vegetable oils are rich in Natural Vitamin E.
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Is Synthetic Vitamin E widely used in supplements?

Yes, due to its cost-effectiveness and stability.
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How does Natural Vitamin E benefit the body?

It supports immune function, skin health, and has antioxidant properties.
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Is Synthetic Vitamin E bad for health?

Not inherently, but it is less potent and bioavailable than Natural Vitamin E.
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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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